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Nursing jobs in Greenville, South Carolina 2026
Metro-level context for Greenville — South Carolina's statewide RN market, top hospitals hiring in the Greenville area, and how the EB-3 sponsorship landscape looks locally.
Metro population
0.9M
RN employed (est.)
9,200
State median salary
$87,670
State shortage
11,800
Top hospitals hiring in Greenville
- • Prisma Health Upstate
- • Bon Secours St. Francis
- • Spartanburg Regional
Why Greenville for international nurses
Greenville is one of South Carolina's largest RN markets with roughly 9,200 registered nurses employed. South Carolina has a 11,800 nurse shortage (12.4% of demand) — an ACTIVE EB-3 sponsorship market with agencies placing overseas-trained nurses in this metro. Median RN salary in the state is $87,670, translating to $73,353 in national purchasing power after cost of living adjustment.